Yhhu 3792

Catalog # Availability Size / Price Qty
Yhhu 3792 | CAS No. 2624336-93-0 | Compounds for NSC Proliferation and Renewal
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Description: Notch signaling pathway activator; enhances the self-renewal capability of NSCs; active in vivo

Chemical Name: 5-(3-Methoxyphenoxy)-N2-[4-(1-methylethyl)phenyl]-2,4-quinazolinediamine hydrochloride

Purity: ≥98%

Product Details

Biological Activity

Yhhu 3792 is a notch signaling pathway activator; enhances the self-renewal capability of neural stem cells (NSCs) via Notch signaling pathway activation in vitro and in vivo. Promotes the expression of Notch target genes, Hes3 and Hes5. Expands the NSCs pool and promotes endogenous neurogenesis in the hippocampal dentate gyrus (DG) after chronic administration in mice. Increases the spatial and episodic memory in mice.

Technical Data

Soluble to 100 mM in DMSO
Store at -20°C

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