YM 155

Catalog # Availability Size / Price Qty
6491/50
6491/10
Cat.No. 6491 - YM 155 | C20H19BrN4O3 | CAS No. 781661-94-7
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Description: Survivin suppressor
Alternative Names: sepantronium bromide

Chemical Name: 4,9-Dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-1H-naphth[2,3-d]imidazolium bromide

Purity: ≥98%

Product Details
Reviews

Biological Activity

Survivin suppressor. Down-regulates survivin expression and sensitizes human NSCLC cell lines to radiation. Enhances radiation-induced tumor regression in nude mice bearing NSCLC xenografts. Also induces apoptosis in TRAIL-resistant glioma cells in vitro.

Technical Data

M.Wt:
443.29
Formula:
C20H19BrN4O3
Solubility:
Soluble to 100 mM in water and to 20 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
781661-94-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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