Biological ActivityZ-VRPR-FMK trifluoroacetate salt is an irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.
This peptide is supplied in gross weight.
Important InformationThis product is sold as a TFA salt. The stoichiometry of the salt and hydration levels vary from batch to batch. This product is sold in gross weight with the batch specific Net Product Content (free base) available on the Certificate of Analysis.
(Modifications: Val-1 = Z-Val, Arg-4 = DL-Arg-fluoromethylketone)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
The proteolytic activity of the paracaspase MALT1 is key in T cell activation.
Rebeaud et al.
Citation for Z-VRPR-FMK trifluoroacetate salt
The citations listed below are publications that use Tocris products. Selected citations for Z-VRPR-FMK trifluoroacetate salt include:
1 Citation: Showing 1 - 1
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