Irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.
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- This peptide is supplied in gross weight.
The proteolytic activity of the paracaspase MALT1 is key in T cell activation.
Rebeaud et al.