Z-VRPR-FMK trifluoroacetate salt

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Z-VRPR-FMK trifluoroacetate salt
1 Image
Description: Irreversible MALT1 inhibitor

Purity: ≥95%

Product Details
Citations (1)

Biological Activity

Z-VRPR-FMK trifluoroacetate salt is an irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.

This peptide is supplied in gross weight.

Important Information

This product is sold as a TFA salt. The stoichiometry of the salt and hydration levels vary from batch to batch. This product is sold in gross weight with the batch specific Net Product Content (free base) available on the Certificate of Analysis.

Technical Data

M. Wt
676.79 (Free Base)

(Modifications: Val-1 = Z-Val, Arg-4 = DL-Arg-fluoromethylketone)

Soluble to 1 mg/ml in water with gentle warming
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under licence from UNIL under the licenced patents

Background References

  1. The proteolytic activity of the paracaspase MALT1 is key in T cell activation.
    Rebeaud et al.
    Nat.Immunol., 2008;9:272

Product Datasheets

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Citation for Z-VRPR-FMK trifluoroacetate salt

The citations listed below are publications that use Tocris products. Selected citations for Z-VRPR-FMK trifluoroacetate salt include:

1 Citation: Showing 1 - 1


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