Catalog Number: 4645
Biological Activity
Irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: Val-1 = Z-Val, Arg-4 = DL-Arg-fluoromethylketone)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under licence from UNIL under the licenced patents
Other Product-Specific Information:
  • This peptide is supplied in gross weight.
Background References
  1. The proteolytic activity of the paracaspase MALT1 is key in T cell activation.
    Rebeaud et al.
    Nat.Immunol., 2008;9:272
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