Zardaverine

  ( 4 citations )    
Product Datasheet
Catalog Number:1046
Chemical Name:6-[4-(Difluoromethoxy)-3-methoxyphenyl]-3(2H)-pyridazinone
Product Details
Citations (4)
Reviews
Biological Activity
Phosphodiesterase inhibitor, selective for PDE3 and 4 (IC50 values are 0.5 and 0.8 μM respectively). Also available as part of the Phosphodiesterase Inhibitor Tocriset™.
Technical Data
  • M.Wt:
    268.22
  • Formula:
    C12H10F2N2O3
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    101975-10-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Zardaverine include:

4 Citations: Showing 1 - 4
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  1. Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine.
    Authors: Navarro Et al.
    J Neurosci  2015;35:6639
  2. The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP.
    Authors: Lee Et al.
    Nature  2012;492:123
  3. Diminished iron concentrations increase adenosine A(2A) receptor levels in mouse striatum and cultured human neuroblastoma cells.
    Authors: Gulyani Et al.
    Exp Neurol  2009;215:236
  4. Ob receptor in rabbit ovary and leptin in vitro regulation of corpora lutea.
    Authors: Zerani Et al.
    Pain  2004;183:279

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