Chemical Name: 6-[4-(Difluoromethoxy)-3-methoxyphenyl]-3(2H)-pyridazinone
Biological ActivityPhosphodiesterase inhibitor, selective for PDE3 and 4 (IC50 values are 0.5 and 0.8 μM respectively).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Is phosphodiesterase inhibition a relevant bronchospasmolytic principle?
Kilian et al.
Agents Actions Suppl., 1989;28:331
Actions of the phosphodiesterase inhibitor zardaverine on guinea pig ventricular muscle.
Galvan and Schudt
Naunyn Schmiedebergs Arch.Pharmacol., 1990;342:221
Citations for Zardaverine
The citations listed below are publications that use Tocris products. Selected citations for Zardaverine include:
4 Citations: Showing 1 - 4
Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine.
Authors: Navarro Et al.
J Neurosci 2015;35:6639
The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP.
Authors: Lee Et al.
Diminished iron concentrations increase adenosine A(2A) receptor levels in mouse striatum and cultured human neuroblastoma cells.
Authors: Gulyani Et al.
Exp Neurol 2009;215:236
Ob receptor in rabbit ovary and leptin in vitro regulation of corpora lutea.
Authors: Zerani Et al.
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