Zardaverine

Key Product Details

Product Description

Zardaverine is a phosphodiesterase inhibitor, selective for PDE3 and 4 (IC₅₀ values are 0.5 and 0.8 μM respectively).

Product Specifications for Zardaverine

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Zardaverine

The following data is based on the product molecular weight 268.22.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

5 4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.73 mL	18.64 mL	37.28 mL
5 mM	0.75 mL	3.73 mL	7.46 mL
10 mM	0.37 mL	1.86 mL	3.73 mL
50 mM	0.07 mL	0.37 mL	0.75 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 38 publications citing the usage of this product.

• Kilian Is phosphodiesterase inhibition a relevant bronchospasmolytic principle? Agents Actions Suppl. 1989 PMID: 2683636
• Galvan and Schudt Actions of the phosphodiesterase inhibitor zardaverine on guinea pig ventricular muscle. Naunyn Schmiedebergs Arch.Pharmacol. 1990 PMID: 1700309

Product Documents for Zardaverine