Home / Inward Rectifier Potassium Channel Activators / ZM 226600

ZM 226600

Catalog #: 0882 Datasheet / COA / SDS

Discontinued Product

0882 has been discontinued.
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ZM 226600 | CAS No. 147695-92-9 | Inward Rectifier Potassium Channel Activators
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Description: Kir6 (KATP) channel opener

Chemical Name: N-(4-Phenylsulfonylphenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide

Product Details
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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

ZM 226600 is a potent Kir6 (KATP) channel opener (EC50 = 0.5 μM), devoid of antiandrogen properties.

Technical Data

M.Wt:
373.35
Formula:
C16H14F3NO4S
Solubility:
Soluble to 100 mM in DMSO
Storage:
Store at RT
CAS No:
147695-92-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the permission of AstraZeneca UK Ltd.

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. Anilide tertiary carbinols: a novel series of K+ channel openers.
    Grant et al.
    TiPS, 1994;15:402

Product Datasheets

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Molarity Calculator

Reconstitution Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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