Webinar: Building Next-Generation Organoid Systems 

Part 1: Building Better Foundations for Organoid Science with Cultrex™ Synthetic Hydrogel

Organoids are powerful models, with applications in drug discovery, personalized medicine, and tissue repair. However, they are often grown using animal-derived matrices like basement membrane extract (BME), which has certain limitations that can increase batch-to-batch variability, skew experimental results, and fail to meet clinical manufacturing standards.

To address this, Cultrex Synthetic Hydrogel was developed as an alternative to BME. It supports the growth of intestinal, liver, pancreatic, and lung organoids while maintaining tissue specific markers and characteristic organoid morphology.

Cultrex Synthetic Hydrogel provides a reliable and consistent solution, improving the reproducibility and applicability of organoid systems for both research and clinical use.

Part 2: Establishing a Biobank of Donor-Matched Normal Lung and Lung Cancer Organoids

Lung cancer in never-smokers is strikingly common in Asia, yet its underlying mechanisms remain poorly understood. To address this gap, a biobank of donor-matched normal and cancerous lung organoids is being established. These models provide a physiologically relevant model that preserves patient-specific genetics and cellular heterogeneity.

This platform enables controlled, long-term studies of environmental impacts on lung carcinogenesis and supports population-specific insights relevant to the region.

Speakers

Dr. Joel Cresser-Brown, PhD
Product Manager, Organoid Team
Bio-Techne

Dr. Xi Lu, PhD 
Senior Scientist
Bio-Techne

Dr. Nathachit Limjunyawong, PhD
Center of Research Excellence in Allergy and Immunology
Department of Immunology, Faculty of Medicine Siriraj Hospital, Thailand