Having trouble trying to find the right product? Chat with our scientists below - we're here to help!
4 results for "PARP" in Products
PARP Products
PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis.
XAV 939 synthesized to cGMP guidelines
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥99% |
Loading...
Biotinylated-NAD+; substrate for ADP-ribosylation
| Chemical Name: | β-Nicotinamide-N6-[2-[[6-[biotinyl]amino]hexyl]amino]-2-oxoethyl]adenine dinucleotide |
Loading...
Potent fluorescent PARP inhibitor; cell permeable
| Alternate Names: | AZD2281-BDY FL,Olaparib-BDY FL |
| Chemical Name: | (T-4)-[4-[[3-[[4-[3-[5-[(3,5-Dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-1H-pyrrol-2-yl-κN-1-oxopropyl]-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinonato]difluoroboron |
| Purity: | ≥90% |
Loading...
Nicotinamide synthesized to Ancillary Material Grade
| Chemical Name: | Pyridine-3-carboxamide |
| Purity: | ≥99% |
Loading...