ACE2 Substrates

ACE2 (E.C. 3.4.17.23), also known as angiotensin-converting enzyme homolog (ACEH) is a single-pass, transmembrane zinc metalloprotease enzyme, found in the lungs, heart, arteries, kidneys, intestines and several brain areas. The protein structure of ACE2 has a single extracellular catalytic domain and a C-terminal transmembrane anchor with a short cytoplasmic tail. ACE2 has a high homology with angiotensin-converting enzyme (ACE) and plays a role in the Renin-Angiotensin System. The primary ...