Angiotensin II
Tocris Bioscience | Catalog # 1158
Potent vasoconstrictor peptide
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Product Description
Angiotensin II is a endogenous potent vasoconstrictor peptide; endogenous substrate for ACE2. Stimulates the synthesis and release of aldosterone.
Product Specifications for Angiotensin II
Molecular Weight
1046.20
Formula
C50H71N13O12
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
4474-91-3
PubChem ID
172198
InChI Key
CZGUSIXMZVURDU-JZXHSEFVSA-N
SMILES
[H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 78 publications citing the usage of this product.
- Mosequeda-Garcia Cardiovascular effects of microinjection of angiotensin II in the brainstem of renal hypertensive rats. J.Pharmacol.Exp.Ther. 1990 PMID: 2213569
- Potts Activation of brain neurons by circulating angiotensin II: direct effects and baroreceptor-mediated secondary effects. Neuroscience 1999 PMID: 10215161
- Clayton Effects of prostaglandins and nitric oxide on the renal effects of angiotensin II in the anaesthetised rat. Br.J.Pharmacol. 1998 PMID: 9723960
Product Documents for Angiotensin II
Product Specific Notices for Angiotensin II
For research use only
Related Research Areas
Citations for Angiotensin II
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Species: RatAssay Type: In VitroCell Line/Tissue: H9C2Verified Customer | Posted 01/05/2018We used this product to treat H9C2 cells to induce the cell hypetrophy and investigate the cell signalling pathway
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