Catalog Number: 1158
Biological Activity
Endogenous potent vasoconstrictor peptide. Stimulates the synthesis and release of aldosterone.
Technical Data
  • M.Wt:
    1046.2
  • Formula:
    C50H71N13O12
  • Sequence:
    DRVYIHPF
  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    4474-91-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Effects of prostaglandins and nitric oxide on the renal effects of angiotensin II in the anaesthetised rat.
    Clayton et al.
    Br.J.Pharmacol., 1998;124:1467
  2. Activation of brain neurons by circulating angiotensin II: direct effects and baroreceptor-mediated secondary effects.
    Potts et al.
    Neuroscience, 1999;90:581
  3. Cardiovascular effects of microinjection of angiotensin II in the brainstem of renal hypertensive rats.
    Mosequeda-Garcia et al.
    J.Pharmacol.Exp.Ther., 1990;255:374
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Angiotensin II include:

5 Citations: Showing 1 - 5
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  1. Acute Metabolic Effects of Olanzapine Depend on Dose and Injection Site.
    Authors: Klingerman Et al.
    Dose Response 2016;13:1559325815618910
  2. The C-terminal module IV of connective tissue growth factor, through EGFR/Nox1 signaling, activates the NF-κB pathway and proinflammatory factors in vascular smooth muscle cells.
    Authors: Rodrigues-Diez Et al.
    Hum Mol Genet 2015;22:29
  3. PCP4: a regulator of aldosterone synthesis in human adrenocortical tissues.
    Authors: Felizola Et al.
    Proc Natl Acad Sci U S A 2014;52:159
  4. Differential effects of alendronate and losartan therapy on osteopenia and aortic aneurysm in mice with severe Marfan syndrome.
    Authors: Nistala Et al.
    J Mol Endocrinol 2010;19:4790
  5. Local IGF-1 isoform protects cardiomyocytes from hypertrophic and oxidative stresses via SirT1 activity.
    Authors: Vinciguerra Et al.
    Aging (Albany NY) 2009;2:43
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