17 results for "Adenosine A2aR Small Molecules and Peptides" in Products
Adenosine A2aR Small Molecules and Peptides
Adenosine A2A Receptor (ADORA2A, Adenosine A2aR) is one of several receptor subtypes for adenosine. The activity of Adenosine A2aR, a G protein-coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. Adenosine A2aR is abundant in basal ganglia, vasculature and platelets and is a major target of caffeine. Variability in the acute blood pressure response to coffee may be partly explained by genetic polymorphisms of the adenosine A2A receptors, including Adenosine A2aR, and alpha(2)-adrenergic receptors.
A2A agonist
| Chemical Name: | 4-[2-[[6-Amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid hydrochloride |
| Purity: | ≥98% |
High affinity adenosine agonist
| Alternate Names: | 5'-N-Ethylcarboxamidoadenosine |
| Chemical Name: | 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-β-D-ribofuranuronamide |
| Purity: | ≥98% |
Potent and highly selective A2A antagonist
| Chemical Name: | 4-(2-[7-Amino-2-(2-furyl)[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethyl)phenol |
| Purity: | ≥98% |
PDE inhibitor (non-selective)
| Chemical Name: | 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione |
| Purity: | ≥98% |
Potent, highly selective A2A antagonist
| Chemical Name: | 2-(2-Furanyl)-7-(2-phenylethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine |
| Purity: | ≥98% |
Very selective, high affinity A2A antagonist
| Chemical Name: | 2-(2-Furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine |
| Purity: | ≥98% |
Endogenous adenosine receptor agonist
| Chemical Name: | 9-β-D-Ribofuranosyl-9H-purin-6-amine |
| Purity: | ≥98% |
A1 and A2B antagonist. CNS stimulant
| Chemical Name: | 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione |
| Purity: | ≥98% |
Potent adenosine receptor antagonist
| Chemical Name: | 9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine |
| Purity: | ≥98% |
Adenosine receptor agonist
| Alternate Names: | 2-CADO |
| Chemical Name: | 6-Amino-2-chloropurine riboside |
| Purity: | ≥98% |
Potent adenosine A2A agonist
| Chemical Name: | 4-[2-[(6-Amino-9-b-D-ribofuranosyl-9H-purin-2-yl)thio]ethyl]benzenesulfonic acid ammonium salt |
| Purity: | ≥97% |
Potent and selective A2A antagonist
| Alternate Names: | KW-6002 |
| Chemical Name: | 8-[(1E)-2-(2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-3,7-dihydro-7-methyl-1H-purine-2,6-dione |
| Purity: | ≥98% |
Adenosine A2A antagonist
| Chemical Name: | 8-Ethoxy-9-ethyl-9H-purin-6-amine |
| Purity: | ≥98% |
Adenosine receptor antagonist
| Chemical Name: | 2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetic acid |
| Purity: | ≥98% |
Potent adenosine A2A and A2B receptor partial agonist
| Chemical Name: | 2-Amino-4-(4-hydroxyphenyl)-6-[(1H-imidazol-2-ylmethyl)thio]-3,5-pyridinecarbonitrile |
| Purity: | ≥98% |
Adenosine receptor antagonist
| Alternate Names: | Xanthine amine congener |
| Chemical Name: | N-(2-Aminoethyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide dihydrochloride |
| Purity: | ≥98% |
Potent and selective A2A antagonist
| Chemical Name: | N-[2-(3,5-Dimethyl-1H-pyrazol-1-yl)-6-[6-(4-methoxy-1-piperidinyl)-2-pyridinyl]-4-pyrimidinyl]acetamide |
| Purity: | ≥98% |
