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2 results for "Androgen Receptor Inhibitors" in Products
Androgen Receptor Inhibitors
Androgen receptors (ARs) (also known as dihydrotestosterone receptors) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid, progesterone and glucocorticoid receptors. They are expressed in bone marrow, mammary gland, prostate, testicular and muscle tissues where they exist as dimers coupled to Hsp90 and HMGB proteins, which are shed upon ligand binding.
Activated androgen receptors bind to nuclear response elements of the genome, with an inverted palindromic ...
Potent, selective human type 1 5α-reductase inhibitor
| Chemical Name: | (4aR,4bS,6aR,7R,9aS,9bS,10S,11aR)-7-[(1R)-1,5-Dimethylhexyl]hexadecahydro-1,4a,6a,10-tetramethyl-2H-indeno[5,4-f]quinolin-2-one |
| Purity: | ≥98% |
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Potent and selective AR and AR L702H Degrader, orally bioavailable
| Chemical Name: | 4-[4-[4-[4-[[4-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-7-methoxy-1-oxo-1H-isoindol-5-yl]-1-piperazinyl]methyl]-1-piperidinyl]phenyl]-1-piperidinyl]-3-fluoro-2-(trifluoromethyl)benzonitrile |
| Purity: | ≥98% |
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