Calsyntenin-3 Products

Calsyntenin-3 (CST-3; also CDH-11 and Alcadein-beta) is a 160 kDa member of the Alcadein family of molecules. It is expressed on the membranes of GABAergic neurons and in the granules of anterior pituitary secretory cells. Calsyntenin-3 is a calcium-binding protein that is proposed to regulate post-synaptic signaling, plus participate in the formation of a membrane-associated APP-X11L-CST-3 complex that blocks APP cleavage.

Mature human CST-3 is a 937 amino acid (aa) type I transmembrane ...