Cannabinoid Transporter Inhibitors Small Molecules and Peptides

Cannabinoid transporters, or AMTs, transport endocannabinoids into cells and limit their activity at CB₁, CB₂ and GPR55 receptors. The action of these putative neurotransmitter transporters facilitates endocannabinoid breakdown by internalizing the molecule and allowing access to fatty acid amide hydrolase (FAAH).

Two endocannabinoids, Anandamide (also known as AEA, Cat. No. 1339) and 2-arachidonoylglycerol (2-AG, Cat. No. 1298), have been identified and since they are widely distributed, it ...