Competitive and selective inhibitor of carrier-mediated anandamide transport (IC50
= 1 μ
M). Does not activate CB1
receptors or inhibit anandamide hydrolysis but has been shown to activate native and cloned vanilloid receptors (pEC50
= 7.4). Active in vivo
. Also available in water soluble emulsion
(Cat. No. 1685).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Functional role of high-affinity anandamide transport, as revealed by selective inhibition.
Beltramo et al.
Potentiation of anandamide hypotension by the transport inhibitor, AM 404.
Calignano et al.
The anandamide transport inhibitor AM404 activates vanilloid receptors.
Zygmunt et al.
Structural determinants for recognition and translocation by the anandamide transporter.
Piomelli et al.
The citations listed below are publications that use Tocris products. Selected citations for AM 404 include:
Showing Results 1 - 10 of 11