5 results for "GPR55 Receptor Agonists" in Products

GPR55 Receptor Agonists

Members of the G protein-coupled receptor (GPCR) family, such as GPR55, play important roles in signal transduction from the external environment to the inside of the cell. GPR55 is a receptor for L-alpha-lysophosphatidylinositol (LPI). LPI induces Ca2+ release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. GPR55 is expressed in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain or in the liver. It is expressed in osteoclasts and osteoblasts. GPR55 may play a role in bone physiology by regulating osteoclast number and function. GPR55 may also be involved in hyperalgesia associated with inflammatory and neuropathic pain.

Potent CB1 antagonist; also GPR55 agonist

Chemical Name: N-(Piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
Purity: ≥98%
Potent CB1 antagonist; also GPR55 agonist
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Selective GPR55 agonist. FAAH and PAA substrate

Alternate Names: PEA
Chemical Name: N-(2-Hydroxyethyl)hexadecanamide
Selective GPR55 agonist. FAAH and PAA substrate
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Potent GPR55 agonist

Chemical Name: 5-Methyl-4-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-1,3-benzenediol
Purity: ≥97%
Potent GPR55 agonist
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Lipid mediator, anorexic actions; also GPR55 and PPARα agonist

Chemical Name: (9Z)-N-(2-Hydroxyethyl)-9-octadecenamide
Purity: ≥99%
Lipid mediator, anorexic actions; also GPR55 and PPARα agonist
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Selective GPR55 agonist; also promotes NSC proliferation and differentiation

Alternate Names: CID 20440433
Chemical Name: 3-[[4-(2,3-Dimethylphenyl)-1-piperazinyl]carbonyl]-N,N-dimethyl-4-(1-pyrrolidinyl)benzenesulfonamide
Purity: ≥98%
Selective GPR55 agonist; also promotes NSC proliferation and differentiation
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