Anandamide

Tocris Bioscience | Catalog # 1339

Endogenous and non-selective CB agonist
Tocris Bioscience

Key Product Details

Description

Endogenous and non-selective CB agonist

Alternative Names

Arachidonylethanolamide,AEA
View all Non-selective Cannabinoid Receptor Agonists »

Product Description

Anandamide is an endogenous cannabinoid and TRPV1 receptor agonist (Ki values are 89 and 371 nM at CB1 and CB2 receptors respectively; EC50 values are 18, 31 and 27 nM at GPR55, CB1 and CB2 respectively; pKi = 5.68 for rTRPV1). Also blocks TNF-α-induced NF-κB activation via direct inhibition of IKK.

Deuterated analog also available.

Product Specifications for Anandamide

Molecular Weight

347.54

Formula

C22H37NO2

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

N-(2-Hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide

CAS Number

94421-68-8

PubChem ID

5281969

InChI Key

LGEQQWMQCRIYKG-DOFZRALJSA-N

SMILES

O=C(NCCO)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 5mg/ml)

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 197 publications citing the usage of this product.

Product Documents for Anandamide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Anandamide

For research use only

Customer Reviews for Anandamide (2)

4.5 out of 5
2 Customer Ratings
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  • Works well for bacterial assays
    Name: Kevin Lorch
    Species: Escherichia coli
    Assay Type: In Vivo
    Verified Customer | Posted 10/05/2022
    Used in a bacterial signaling assay to screen for potential sensors of anandamide. Very easy to work with, non-toxic to E. coli even at concentrations up to 1 mg/mL. Planning to reorder for some follow-up experiments. Only downside is having to store at -80C.
  • test
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 08/10/2020
    Diluted it in ethanol and kept it at -20 C until needed to use.
    Performed an exposure using different concentrations of anandamide. Didn't have any issues diluting it.

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