4 results for "CAR/NR1I3 Small Molecules and Peptides" in Products

CAR/NR1I3 Small Molecules and Peptides

CAR, (MB67; NR1I3) is a 40 kDa member of the NR1 subfamily of the nuclear hormone receptor family. CAR is predominantly expressed in the liver and forms a heterodimer with RXR. The CAR/RXR heterodimer activates retinoic acid, xenobiotic and phenobarbital response elements. There are two isoforms of the CAR nuclear hormone receptor. Each contains a ...

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Potent liver X receptor (LXR) agonist; also CAR inverse agonist

Chemical Name: N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzenesulfonamide
Purity: ≥98%
Potent liver X receptor (LXR) agonist; also CAR inverse agonist
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Selective CAR agonist

Chemical Name: 6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)oxime
Purity: ≥98%
Selective CAR agonist
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Cytochrome P450 inhibitor; antifungal

Alternate Names: CLT
Chemical Name: 1-(2-Chloro-α,α-diphenylbenzyl)imidazole
Purity: ≥98%
Cytochrome P450 inhibitor; antifungal
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Human pregnane X receptor agonist; H1 antagonist

Alternate Names: Meclozine
Chemical Name: 1-[(4-Chlorophenyl)phenylmethyl]4-[(3-methylphenyl)methyl]piperazine dihydrochloride
Purity: ≥99%
Human pregnane X receptor agonist; H1 antagonist
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