2 results for "CCR5 Small Molecules and Peptides" in Products

CCR5 Small Molecules and Peptides

CCR5 is a G protein-coupled receptor member of the CC chemokine subfamily of receptors. Human CCR5 is 352 amino acids (aa) in length with a predicted molecular weight of 40 kDa. Mouse and rat CCR5 share 82% aa sequence identity with the human protein. Most chemokine receptors exhibit promiscuous binding properties whereby several different chemokin...

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Selective CCR5 antagonist

Alternate Names: UK-427857
Chemical Name: 4,4-Difluoro-N-{(1S)-3-[3-(3-isopropyl- 5-methyl-4H-1,2,4-triazol-4-yl)- 8-azabicyclo[3.2.1]oct-8-yl]-1- phenylpropyl}cyclohexanecarboxamide
Purity: ≥98%
Selective CCR5 antagonist
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Potent and selective CCR5 and CCR2 chemokine receptor antagonist

Chemical Name: N-[[4-[[[6,7-Dihydro-2-(4-methylphenyl)-5H-benzocyclohepten-8-yl]carbonyl]amino]phenyl]methyl]tetrahydro-N,N-dimethyl-2H-pyran-4-aminium chloride
Purity: ≥98%
Potent and selective CCR5 and CCR2 chemokine receptor antagonist
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