CL-P1/COLEC12 Proteins and Enzymes

Collectins are a family of Ca++-dependent, C-type lectins that contain a collagenous domain and function as recognition molecules for molecular patterns found on pathogens. Human collectin placenta 1 [CL-P1; also known as collectin sub-family member 12 and SRCL type I (scavenger receptor with C-type lectin type I)] is a 110 kDa member of the collectin family of glycoproteins. With two exceptions, all collectins are secreted. CL-P1 is the only collectin known to be membrane bound, while CL-L1 (collectin liver-1) is the only known cytoplasmic collectin.