Dkk-3 Proteins and Enzymes

Dkk-3, also known as REIC, is a member of the Dickkopf family of secreted Wnt antagonists. Dkk-3 is expressed most strongly in adult heart, brain, and spinal cord as well as during early embryonic development. Dkk-3 is downregulated in many tumors which often is correlated with faster tumor progression and shorter survival. The prototype Dickkopf m...