Dopamine Transporter Inhibitors Fluorescent Probes and Dyes

Dopamine transporters (DAT) are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6) widely distributed throughout the brain in areas of dopaminergic activity, including the striatum and substantia nigra. They provide rapid clearance of dopamine, adrenalin and noradrenalin from the synaptic cleft, terminating the neurotransmitter signal.

Dopamine transporters can also mediate an outward efflux and it has been suggested that inward and outward transport are independently ...