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1 result for "EGLN2/PHD1 Small Molecules and Peptides" in Products
EGLN2/PHD1 Small Molecules and Peptides
EGLN2 (EGL/EGg Laying-Nine #2; also known as PHD1 and HPH3) is a 43 kDa member of the EglN family of proteins. It is ubiquitously expressed and found principally in the nucleus. EGLN2 hydroxylates proline on HIF-1 alpha. HIF-1 is an alpha/beta heterodimeric transcriptional activator that upregulates genes involved in mitigating the effects of hypox...
Potent, selective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor
| Chemical Name: | N-[[1,2-Dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]glycine |
| Purity: | ≥98% |
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