2 results for "Ferroptosis Inhibitors" in Products

Ferroptosis Inhibitors

Ferroptosis is a form of regulated cell death, distinct from apoptosis, necroptosis and autophagy. It is an iron-dependent process that results from the loss of glutathione peroxidase 4 (GPX4) activity, leading to accumulation of lipid peroxidation products and reactive oxygen species (ROS).

GPX4 is a selenoprotein that reduces hydrogen peroxide and lipid peroxides, while converting reduced glutathione (GSH) to its oxidized form; oxidized glutathione (glutathione disulfide) is recycled by ...

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Ferroptosis suppressor protein 1 (FSP1) inhibitor; ferroptosis inducer

Chemical Name: 1-Amino-3-(4-methylphenyl)-pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile
Purity: ≥98%
Ferroptosis suppressor protein 1 (FSP1) inhibitor; ferroptosis inducer
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Induces ferroptosis; inhibits FSP1

Chemical Name: 3-(4-Bromophenyl)-6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)thiazolo[2,3-c][1,2,4]triazole
Purity: ≥98%
Induces ferroptosis; inhibits FSP1
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