Furin Proteins and Enzymes

Furin is a member of the proprotein convertase family of serine proteases. Furin processes a variety of proproteins in secretory pathway compartments by cleaving after Arg-Xaa-Lys/Arg-Arg-like motifs. It acts on the pro-forms of multiple growth factors and receptors, extracellular matrix proteins, as well as other proteases. Furin has an essential ...