5 results for "GDF-8/Myostatin ELISA Kits" in Products
GDF-8/Myostatin ELISA Kits
GDF-8/Myostatin is a secreted protein that is expressed in developing and adult skeletal muscle. It controls myoblast proliferation and is a potent negative regulator of skeletal muscle mass. It is upregulated in mechanically-stressed cardiomyocytes and induces the skeletal muscle wasting which is common in heart failure. The GDF-8 propeptide is cleaved from GDF-8 but remains associated and functions as an inhibitor of mature GDF-8. GDF-8 activity can also be inhibited through its association with Follistatin, FLRG, Decorin, or GASP-1. Active GDF-8 signals through a receptor complex containing Activin RIIB and either Activin RIB/ALK-4 or TGF-beta RI/ALK-5.
For use with catalog number DGDF80
| Reactivity: | Human |
| Applications: | Ctrl |
| Reactivity: | Monkey |
| Sensitivity: | 0.47 ng/mL |
| Assay Range: | 0.78 - 50 ng/mL |
| Applications: | ELISA |
| Reactivity: | Porcine |
| Sensitivity: | 53 pg/mL (example only; lot dependent) |
| Assay Range: | 125 - 8000 pg/mL (example only; lot dependent) |
| Applications: | ELISA |
| Reactivity: | Multi-Species |
| Sensitivity: | 5.32 pg/mL |
| Assay Range: | 31.3-2000 pg/mL (Cell Culture Supernates, Tissue Homogenates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications: | ELISA |
| Reactivity: | Multi-Species |
| Assay Range: | 31.2-2000 pg/mL |
| Applications: | ELISA |
