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2 results for "Glutaminase Inhibitors Small Molecules and Peptides" in Products
Glutaminase Inhibitors Small Molecules and Peptides
Glutaminase (GLS) is an aminohydrolase enzyme, EC 3.5.1.2, which catalyzes the conversion of the amino acid glutamine to glutamate. Two GLS isoforms have been identified to date, GLS1 (KGA; kidney-type glutaminase) and GLS2 (LGA; liver-type glutaminase). There is also a shorter splice variant of GLS1, named glutaminase C (GAC). GLS2 is predominantly expressed in the liver, whereas GLS1 and GAC have a ubiquitous tissue distribution.
GLS is activated by inorganic phosphate, which causes inactive ...
Selective allosteric glutaminase (GLS1) inhibitor
| Chemical Name: | N,N'-[Thiobis(2,1-ethanediyl-1,3,4-thiadiazole-5,2-diyl)]bisbenzeneacetamide |
| Purity: | ≥90% |
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Potent glutaminase GLS1 inhibitor
| Chemical Name: | N-[5-[4-[6-[[2-[3-(Trifluoromethoxy)phenyl]acetyl]amino]-3-pyridazinyl]butyl]-1,3,4-thiadiazol-2-yl]-2-pyridineacetamide |
| Purity: | ≥98% |
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