4 results for "Histone Deacetylase Degraders" in Products

Histone Deacetylase Degraders

Potent and selective HDAC4 Degrader (PROTAC®)

Chemical Name: (2S,4R)-1-((3R,26S)-26-(tert-Butyl)-3-methyl-1,24-dioxo-5-propyl-1-(4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenyl)-10,13,16,19,22-pentaoxa-2,5,25-triazaheptacosan-27-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥98%
Potent and selective HDAC4 Degrader (PROTAC®)
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Potent and selective HDAC8 degrader (PROTAC®)

Chemical Name: 3-((4-((8-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)octyl)carbamoyl)benzyl)oxy)-N-hydroxy-4-methoxybenzamide
Purity: ≥98%
Potent and selective HDAC8 degrader (PROTAC®)
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Selective class I HDAC Degrader (PROTAC®)

Chemical Name: (2S,4R)-1-((S)-2-(2-((9-(2-((4-((2-Aminophenyl)carbamoyl)phenyl)amino)-2-oxoethoxy)nonyl)oxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥97%
Selective class I HDAC Degrader (PROTAC®)
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Selective HDAC3 Degrader (PROTAC®)

Chemical Name: (2S,4R)-N-[2-[[12-[[4-[(2-Aminophenyl)carbamoyl]phenyl]amino]-12-oxododecyl]oxy]-4-(4-methylthiazol-5-yl)benzyl]-1-[(S)-2-(1-fluorocyclopropan-1-ylcarbonylamino)-3,3-dimethylbutanoyl]-4-hydroxypyrrolidine-2-carboxamide
Purity: ≥98%
Selective HDAC3 Degrader (PROTAC®)
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