HOXB8 Proteins and Enzymes

HOXB8 is 243 amino acids long, weighing approximately 27.5 kDa, that functions as a sequence-specific transcription factor which focuses on the specific positional identities of cells on the anterior-posterior axis, which is all part of a developmental regulatory system. Current studies are being done on several diseases and disorders including colorectal cancer, neuroblastoma, and neuronitis. HOXB8 has also been shown to have interactions with MEIS1, PBX2, PBX1, PBX3, and ASB1.