Hyaluronidase 2/HYAL2 Proteins and Enzymes

HYAL2 (Hyaluronoglucosaminidase 2) is involved in glycosaminoglycan catabolism. HYAL2 has been associated with tumor suppression due to its location in a region of chromosome 3p21.3. HYAL2 is known to have interactions with MST1R, ERVW-1, ARSB, CD44 and HMMR. HYAL2 has been studied in relation to several diseases and disorders including lung carcinoma, breast cancer, COPD, gastric cancer, endometrial cancer, Non-Hodgkin lymphoma, rheumatoid arthritis, Hodgkin's lymphoma and osteoarthritis.