1 result for "IAP Inhibitors" in Products

IAP Inhibitors

Inhibitors of apoptosis (IAP) are a family of proteins that are the major regulators of apoptosis through their interaction with the various components of the apoptotic signaling cascades. Originally discovered in baculovirus, the human homologs are sometimes described as baculovirus IAP repeat containing (BIRC) proteins.

There are a number of different IAPs including neuronal apoptosis inhibitory protein (NAIP or BIRC1), cellular IAPs (c-IAP-1 and c-IAP-2, or BIRC2 and BIRC3 respectively), ...

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Functionalized IAP ligand for PROTACs®

Chemical Name: tert-Butyl ((S)-1-(((S)-1-cyclohexyl-2-((2S,4S)-4-(3-hydroxyphenoxy)-2-(((R)-1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)pyrrolidin-1-yl)-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate
Purity: ≥95%
cIAP1 PROTAC® Degrader
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