1 result for "IL-8/CXCL8 Small Molecules and Peptides" in Products

IL-8/CXCL8 Small Molecules and Peptides

Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXC...

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Active metabolite binds CPSF3; Pro-drug

Alternate Names: TO-207
Chemical Name: N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride
Purity: ≥98%
Active metabolite binds CPSF3; Pro-drug
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