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1 result for "Inflammasomes Inhibitors" in Products
Inflammasomes Inhibitors
A canonical inflammasome consists of a sensor molecule, which binds to caspase 1 via the adaptor protein ASC (apoptosis-associated speck-like protein). The exact composition of the inflammasome is determined by the type of activator. The most common sensor molecules are NOD-like receptors (NLRs); these include the subtypes NLRP1 (NOD-, LRR- and pyrin domain-containing 1), NLRP3, NLRP6, NLRP7, NLRP12, AND NLRC4 (NOD-, LRR- and CARD-containing 4; IPAF). Other sensor molecules include PYHIN, AIM2 ...
Potent NLRP3 inflammasome inhibitor; inhibits IL-1β production
| Alternate Names: | CP-456773,MCC 950 |
| Chemical Name: | N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide sodium salt |
| Purity: | ≥98% |
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