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2 results for "Lactate Dehydrogenase A/LDHA Inhibitors" in Products
Lactate Dehydrogenase A/LDHA Inhibitors
Lactate Dehydrogenase A (LDHA; LDH5), EC 1.1.1.27, is one of five isoforms of the lactate dehydrogenase family. It catalyzes the conversion of pyruvate to lactate under anaerobic conditions and plays a key role in the altered glycolytic metabolism that is a feature of cancer cells. LDHs are tetrameric enzymes comprising two different types of subunit, M and H; different combinations of these subunits result in five separate isoforms. LDHA, which is found mainly in skeletal muscle but also in ...
Potent and selective LDHA inhibitor
| Chemical Name: | 3-[[3-[(Cyclopropylamino)sulfonyl]-7-(2,4-dimethoxy-5-pyrimidinyl)-4-quinolinyl]amino]-5-(3,5-difluorophenoxy)benzoic acid |
| Purity: | ≥98% |
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LDHA inhibitor
| Chemical Name: | Methyl 1-hydroxy-6-phenyl-4-(trifluoromethyl)-1H-indole-2-carboxylate |
| Purity: | ≥98% |
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