LDHA inhibitor; reduces lactate production in HeLa cells. Inhibits cell growth of LPC006 and PANC-1 cells in vitro
. Also enhances the antiproliferative effects of Gemcitabine
(Cat. No. 3259) on LPC006 and PANC-1 cells.
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All Tocris products are intended for laboratory research use only.
Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia.
Maftouh et al.
Dual targeting of the Warburg effect with a glucose-conjugated lactate dehydrogenase inhibitor.
Calvaresi et al.
Assessing the differential action on cancer cells of LDH-A inhibitors based on the N-hydroxyindole-2-carboxylate (NHI) and malonic (Mal) scaffolds.
Granchi et al.