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2 results for "LPAR5/LPA5/GPR92 Small Molecules and Peptides" in Products
LPAR5/LPA5/GPR92 Small Molecules and Peptides
LPAR5/LPA5/GPR92 is a member of the rhodopsin class of G protein-coupled receptors (GPCRs). This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. GPR92 is abundantly expressed by human mast cells and important for lysophosphatidic acid induced MIP-1 beta release. GPR92 expression in chronic lymphocytic leukemia leads to cell survival mediated though vascular endothelial growth factor (VEGF) expression.
LPA5 receptor antagonist
| Chemical Name: | 5-(3-Chloro-4-cyclohexylphenyl)-1-(3-methoxyphenyl)-1H-pyrazole-3-carboxylic acid |
| Purity: | ≥98% |
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Selective, brain penetrant LPA5 antagonist
| Chemical Name: | 6,7-Dimethoxy-2-(5-methyl-1,2-benzisoxazol-3-yl)-4-(1-piperidinylcarbonyl)-1(2H)-isoquinolinone |
| Purity: | ≥98% |
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