Myosin Inhibitors

Myosins are a large family of motor proteins that share the common features of ATP hydrolysis (ATPase enzyme activity), actin binding and potential for kinetic energy transduction. Originally isolated from muscle cells (hence the name), almost all eukaryotic cells are now known to contain myosins.

Structurally, mysoins contain a 'head' domain that binds to actin filaments (microfilaments) and is the site of ATP hydrolysis. The 'tail' domain interacts with cargo molecules, and the ...