2 results for "Nicotinic Acetylcholine R beta 4/CHRNB4 Small Molecules and Peptides" in Products

Nicotinic Acetylcholine R beta 4/CHRNB4 Small Molecules and Peptides

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero) pentamers composed of homologous subunits. After binding acetylcholine, the nAChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Non-competitive nAChR antagonist

Chemical Name: (1R,2S,4S)-rel-N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride
Non-competitive nAChR antagonist
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Potent and selective neuronal nAChRagonist

Chemical Name: (1R,5S)-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one
Purity: ≥99%
Potent and selective neuronal nAChRagonist
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