Mecamylamine hydrochloride

Key Product Details

Product Description

Mecamylamine hydrochloride is a non-competitive nicotinic acetylcholine receptor antagonist. Displays antidepressant-like effects in mice.

Product Specifications for Mecamylamine hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Mecamylamine hydrochloride

The following data is based on the product molecular weight 203.75.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

5 4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.91 mL	24.54 mL	49.08 mL
5 mM	0.98 mL	4.91 mL	9.82 mL
10 mM	0.49 mL	2.45 mL	4.91 mL
50 mM	0.10 mL	0.49 mL	0.98 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 83 publications citing the usage of this product.

• Rabenstein The nicotinic antagonist mecamylamine has antidepressant-like effects in wild-type but not β2- or α7-nicotinic acetylcholine receptor subunit knockout mice. Psychopharmacol.
• Ostroumov Modeling study of mecamylamine block of muscle type acetylcholine receptors. Eur.Biophys.J. 2007 PMID: 17938901

Product Documents for Mecamylamine hydrochloride