Non-competitive nicotinic acetylcholine receptor antagonist. Displays antidepressant-like effects in mice.
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Modeling study of mecamylamine block of muscle type acetylcholine receptors.
Ostroumov et al.
The nicotinic antagonist mecamylamine has antidepressant-like effects in wild-type but not β2- or α7-nicotinic acetylcholine receptor subunit knockout mice.
Rabenstein et al.
The citations listed below are publications that use Tocris products. Selected citations for Mecamylamine hydrochloride include:
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