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1 result for "NLRP3/NALP3" in Products
NLRP3/NALP3 Products
NALP3 (NAcht Leucine-rich repeat Protein 3), also known as CIAS1, PYPAF or Cryopyrin is a cytosolic ~120 kDa member of the NLRP family of proteins expressed in leukocytes, especially neutrophils. As a component of the inflammasome, NALP3 activates caspases 1 and 5. Defects in NALP3 may cause FCAS1, CINCA, or Muckle-Wells autoinflammatory syndromes.
| Alternate Names: | CP-456773,MCC 950 |
| Chemical Name: | N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide sodium salt |
| Purity: | ≥98% |
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