1 result for "NUAK2 Small Molecules and Peptides" in Products

NUAK2 Small Molecules and Peptides

Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment byincreasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cellsfrom CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells

Potent and selective NUAK1/2 inhibitor

Chemical Name: N-3-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]propanamide
Purity: ≥98%
Potent and selective NUAK1/2 inhibitor
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