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2 results for "PARP6" in Products
PARP6 Products
Poly (ADP-ribose) polymerase (PARP) catalyzes the post-translational modification of proteins by the addition of multiple ADP-ribose moieties. PARP transfers ADP-ribose from nicotinamide dinucleotide (NAD) to glu/asp residues onthe substrate protein, and also polymerizes ADP-ribose to form long/branched chain polymers. PARP inhibitors are beingdeveloped for use in a number of pathologies including cancer, diabetes, stroke and cardiovascular disease.
Potent PARP inhibitor
| Chemical Name: | N-(5,6-Dihydro-6-oxo-2-phenanthridinyl)-2-acetamide hydrochloride |
| Purity: | ≥98% |
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PARP inhibitor; photoaffinity probe
| Chemical Name: | 3-(3-Butyn-1-yl)-N-[5-cyano-6-[4-[3-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]benzoyl]-1-piperazinyl]-3-pyridinyl]-3H-diazirine-3-propanamide |
| Purity: | ≥95% |
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