1 result for "PD-1 Proteome Profiler Antibody Arrays" in Products

PD-1 Proteome Profiler Antibody Arrays

PD-1 (Programmed Death-1 receptor) is a key regulator of the threshold of immune response and peripheral immune tolerance. It is expressed on activated T cells, B cells, monocytes, and dendritic cells and binds to PD-L1 or PD-L2. PD-1 ligation induces co-inhibitory signals in T cells promoting their apoptosis, anergy, and functional exhaustion. Man...

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Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies

Reactivity: Human
Applications:
The Human Phospho-Immunoreceptor Array detects multiple tyrosine phosphorylated immunoreceptors in lysates prepared from cells activated by antibody mediated cross-linking of cell-surface immunoreceptors.
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