2 results for "PLA2G4A Small Molecules and Peptides" in Products

PLA2G4A Small Molecules and Peptides

Secretory phopholipase A2 (PLA2) enzymes cleave an acyl ester bond in the sn-2 position of glycerophospholipids. These extracellular proteins have a high disulfide bond content, low molecular mass (14 kDa), and require mM levels of Ca2+ for catalysis. They play a crucial role in the generation of arachidonates and eicosanoids, and have a number of ...

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Phospholipase A2 inhibitor

Alternate Names: Arachidonyl trifluoromethyl ketone
Chemical Name: 1,1,1-Trifluoro-6Z,9Z,12Z,15Z-heneicosateraen-2-one
Phospholipase A2 inhibitor
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Potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor; active in vivo; orally bioavailable

Chemical Name: 3-(3-Phenethyl-1-(4-phenoxyphenyl)-1H-indol-5-yl)propanoic acid tris salt
Purity: ≥98%
Potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor; active in vivo; orally bioavailable
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