PPP4R4 Proteins and Enzymes

The protein encoded by the PPP4R4 gene is a HEAT-like repeat-containing protein. The HEAT repeat is a tandemly repeated,37-47 amino acid long module occurring in a number of cytoplasmic proteins. Arrays of HEAT repeats form a rod-likehelical structure and appear to function as protein-protein interaction surfaces. The repeat-containing region of thisprotein has some similarity to the constant regulatory domain of the protein phosphatase 2A PR65/A subunit. Thefunction of this particular gene product has not been determined. Alternative splicing has been observed for this geneand two transcript variants encoding distinct isoforms have been identified. (provided by RefSeq)