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1 result for "PTIP Proteins and Enzymes" in Products
PTIP Proteins and Enzymes
PTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. Tandem BRCT (BRCA1 carboxyl-terminal) domains in PTIP and in BRCA1 serve as phosphoserine or phosphothreonine specific binding modules that recognize substrates phosphorylated by the kinases ATM and ATR in response to gamma irradiation.
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
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