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2 results for "ROR / NR1F Inverse Agonists Small Molecules and Peptides" in Products
ROR / NR1F Inverse Agonists Small Molecules and Peptides
Retinoic acid-related Orphan Receptors (RORs) are a family of orphan nuclear receptors that are believed to play a role in numerous physiological processes, including circadian rhythm and bone metabolism. The endogenous ligand for these receptors is not yet known.
Three members of the ROR family have been identified: RORα, RORβ and RORγ. RORα shows the highest expression levels in the cerebellum and thalamus, whilst RORβ is expressed in a more restricted fashion in the ...
Selective RORγ inverse agonist
| Chemical Name: | 2-Fluoro-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-a,a-bis(trifluoromethyl)-[1,1'-biphenyl]-4-methanol |
| Purity: | ≥98% |
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RORγt inverse agonist; suppresses Th17 cell differentiation
| Chemical Name: | 3-(1,3-Benzodioxol-5-yl)-1-(cis-3,5-dimethyl-1-piperidinyl)-3-(2-hydroxy-4,6-dimethoxyphenyl)-1-propanone |
| Purity: | ≥98% |
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