1 result for "RUNX1/CBFA2 Small Molecules and Peptides" in Products

RUNX1/CBFA2 Small Molecules and Peptides

Runt-related transcription factor 2 (RUNX1), also called CBFA2, is a DNA-binding subunit that heterodimerizes with CBF-beta to form a transcription factor that plays a role in normal hematopoiesis. Defects in CBFA2 are associated with several types of leukemia.

Core binding factor inhibitor; attenuates hematopoiesis

Alternate Names: CBF&#946-Runx1 inhibitor II
Chemical Name: 7-Chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-2H-1,4-benzodiazepin-2-one
Purity: ≥98%
Core binding factor inhibitor; attenuates hematopoiesis
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