2 results for "Secretase Inhibitors" in Products

Secretase Inhibitors

γ-secretase is a multi-subunit internal protease that cleaves within the transmembrane domain of its substrates. It is an integral membrane protein and minimally consists of four proteins; presenilin, nicastrin, APH-1 and PEN-2. Presenilin is an aspartic protease and the catalytic subunit of the complex.

γ-secretase is involved in the processing of Notch. The Notch receptor is a single transmembrane spanning protein involved in angiogenesis and cell differentiation during embryonic ...

Show More

γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling

Chemical Name: (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester
Purity: ≥99%
Using DAPT to differentiate hiPSCs into dopaminergic neurons
(2)
Loading...

DAPT synthesized to Ancillary Material Grade

Chemical Name: (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenylglycine 1,1-dimethylethyl ester
Purity: ≥99%
DAPT synthesized to Ancillary Material Grade
Loading...
Results Per Page
5 10 25 50
  • / 1