SLIRP Proteins and Enzymes

SLIRP (SRA stem-loop interacting RNA binding protein) is expressed in normal and tumor tissues, but the majority of the endogenous SLIRP resides in the mitochondria. SLIRP may regulate mitochondrial functions and has the potential to shut down oestrogen in breast cancer cells and testosterone in prostate cancer cells. SLIRP has also been shown to turn down genes involved in energy metabolism.