t-Plasminogen Activator/tPA Activity Assays

tPA (tissue-type Plasminogen Activator) is a serine protease that is secreted by vascular endothelial cells, fibroblasts, neurons, microglia, and astrocytes. The partially active single chain can be further processed to full activity by Plasmin, Kallikrein 1, or Coagulation Factor Xa.  Active tPA converts Plasminogen to Plasmin, a fibrino...